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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNRNPC
All Species:
9.09
Human Site:
S185
Identified Species:
25
UniProt:
P07910
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.75
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07910
NP_001070910.1
306
33670
S185
G
Q
R
G
S
S
K
S
G
K
L
K
G
D
D
Chimpanzee
Pan troglodytes
XP_001152335
293
32198
S172
G
K
R
G
S
S
K
S
G
K
L
K
G
D
D
Rhesus Macaque
Macaca mulatta
XP_001096688
307
33803
S186
G
Q
R
G
S
S
K
S
G
K
L
K
G
D
D
Dog
Lupus familis
XP_851458
302
33240
K180
G
Q
R
G
S
S
S
K
S
G
K
L
K
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z204
313
34366
K185
G
Q
R
G
S
S
S
K
S
G
K
L
K
G
D
Rat
Rattus norvegicus
NP_001020804
298
32839
K172
G
Q
R
G
S
S
S
K
S
V
K
G
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511210
307
33796
K185
G
Q
R
G
S
S
S
K
S
G
K
L
K
G
D
Chicken
Gallus gallus
Frog
Xenopus laevis
P19600
282
30931
K171
G
Q
R
G
G
S
S
K
S
S
R
L
K
G
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24491
197
21114
R102
G
R
R
G
D
F
G
R
H
S
I
T
S
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
98.6
96.7
N.A.
95.5
92.1
N.A.
97.7
N.A.
75.8
N.A.
N.A.
21.2
N.A.
N.A.
N.A.
Protein Similarity:
100
89.8
99
97.3
N.A.
96.4
93.4
N.A.
98.6
N.A.
83
N.A.
N.A.
31.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
46.6
N.A.
46.6
46.6
N.A.
46.6
N.A.
40
N.A.
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
46.6
N.A.
46.6
N.A.
40
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
0
12
45
78
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
0
0
100
12
0
12
0
34
34
0
12
34
56
12
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
34
56
0
34
45
34
45
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
34
45
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
100
0
0
0
0
12
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
78
89
56
34
56
23
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _